Gold nanoparticles functionalized with cresyl violet and porphyrin via hyaluronic acid for targeted cell imaging and phototherapy.
نویسندگان
چکیده
Gold nanoparticles are functionalized as a nanoprobe with cresyl violet and porphyrin via hyaluronic acid. The nanoprobe becomes highly fluorescent in the presence of hyaluronidase or under ultraviolet irradiation, and can be used to target cancer cells via the overexpressed CD44 receptor for fluorescence imaging and phototherapy.
منابع مشابه
Folic acid-modified diatrizoic acid-linked dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human cervical cancer
متن کامل
Synthesis of size-tunable chitosan encapsulated gold-silver nanoflowers and their application in SERS imaging of living cells.
Anisotropic metallic nanoparticles (NPs) possess unique optical properties, which lend them to applications such as surface-enhanced Raman scattering (SERS). However, their preparation by an efficient, biocompatible and high yield synthetic method is still challenging. In this work, we demonstrate a simple and reproducible way to produce chitosan (CS) encapsulated gold-silver nanoflowers by seq...
متن کاملEvaluation of multifunctional targeted gold nanoparticles on X-ray attenuation in nasopharyngeal cancer cells by X- ray imaging
Introduction: Head-and-neck cancer is the sixth most common cancer worldwide with the number of cases consistently increasing in developing countries. Successful development of effective, safe and cost effective nanoprobes for head-and-neck cancer targeting imaging is a big challenge. This study is aimed to develop cysteamine-folate conjugated gold nanoparticles (F-Cys-AuNPs) a...
متن کاملSynthesis and Functionalization of Gold Nanoparticles by Using of Poly Functional Amino Acids
Synthesis and characterization of two functionalized gold nanoparticles by using of two poly functional amino acids (L-Arginine and L-Aspartic acid) are reported. The gold nanoparticles were reduced by sodium citrate and functionalized with L-Arginine at the pH of 7 and 11 and L-Aspartic acid at the pH of 7. Transmission electron microscopy, UV-Vis spectroscopy, dynamic light scattering, zeta p...
متن کاملHyaluronic acid-functionalized bismuth oxide nanoparticles for computed tomography imaging-guided radiotherapy of tumor
The inherent radioresistance and inaccuracy of localization of tumors weaken the clinical implementation effectiveness of radiotherapy. To overcome these limitations, hyaluronic acid-functionalized bismuth oxide nanoparticles (HA-Bi2O3 NPs) were synthesized by one-pot hydrothermal method for target-specific computed tomography (CT) imaging and radiosensitization of tumor. After functionalizatio...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 50 99 شماره
صفحات -
تاریخ انتشار 2014